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P Microbial pathogenesis training group
publications

29. Tan Y. Arnold A. J. and Luo Z.-Q. 2011. Legionella pneumophila regulates the small GTPase Rab1 activity by reversible phosphorylcholination. Proc. Natl. Acad. Sci. USA. 108:21212-7 PMID: 22158903

28. Luo Z.-Q. 2012. Legionella secreted effectors and innate immune responses. Cellular Microbiology (invited review). 14:19-27. PMID: 21985602

27. Tan Y. and Luo Z.-Q. 2011. Take it and release it: the use of the Rab1 small GTPase at a bacterium's will. Cellular Logistics (invited review). 1:4, 1-3.

26. Jain, P., Luo, Z.-Q., & Blanke, S. R. 2011. Helicobacter pylori VacA engages the mitochondrial apoptotic machinery by inducing Drp1-mediated mitochondrial fission. Proc. Natl. Acad. Sci. U S A. 108:16032-7. PMID: 21903925

25. Tan Y. and Luo Z.-Q. 2011. Legionella pneumophila SidD is a deAMPylase that modifies Rab1. Nature. 475:506-509. PMID: 21734656 (cited by Faculty 1000 as a must read article).

24. Zhu W., Banga S., Tan Y., Zheng C., Stephenson R., Gately J. and Luo Z.-Q. 2011. Comprehensive identification of protein substrates of the Dot/Icm type IV transporter of Legionella pneumophila.  PLoS One .6(3):e17638. PMID: 21408005

23. Luo Z.-Q. Striking a balance: Modulation of host cell death pathways by Legionella pneumophila. 2011. Front. Microbio. doi: 10.3389/fmicb.2011.00036 PMID: 21687427 (invited review).

22. Luo Z.-Q. 2011.Targeting one of its own: expanding roles of substrates of the Legionella pneumophila Dot/Icm type IV secretion system. 2011. Front. Microbio. 2:31. doi: 10.3389/fmicb.00031 PMID: 21687422 (invited commentary).

21. Fontana M. F., Banga S., Barry K. C., Shen X., Tan, Y., Luo Z.-Q*. and Vance E.V*.  2011. Secreted bacterial effectors that inhibit host protein synthesis are critical for induction of the innate immune response to virulent Legionella pneumophila.  PLoS Pathogens. 7: e1001289. PMID: 21390206 (*, co-corresponding authors)

20. Chen C†. Banga, S†., Mertens, K†., Weber M., Gorbaslieva, I.,Tan Y., Luo, Z.-Q*. and Samuel J. E. * 2010 Large-scale identification and translocation of Type IV secretion substrates by Coxiella burnetii Proc Natl Acad Sci USA. 107:21755-21760. †, equal contribution authors *,co-corresponding authors

19. Mei G.Y, Yan X. X, Turak A, Luo Z.-Q, Zhang L. Q. 2010.  AidH, an alpha/beta-hydrolase fold family member from an Ochrobactrum sp. strain, is a novel N-acylhomoserine lactonaseAppl Environ Microbiol. 76:4933-42. PMID: 20525860

18. Xu L., Shen X., Bryan A., Banga S., Swanson M. and Luo ZQ. 2010. Inhibition of host vacuolar H+-ATPase activity by a Legionella pneumophila effector PLoS Pathogens 19;6(3):e1000822. PMID: 20333253

17. Shen X., Banga S., Liu Y., Xu L., Gao P., Shamovsky I., Nudler E. and Luo Z.-Q. 2009. Targeting eEF1A by a Legionella pneumophila effector leads to inhibition of protein synthesis and induction of host stress response. Cellular Microbiology. 11: 911-926. PMID: 19386084

16. Liu Y., Gao P. Banga S. and Luo Z.-Q.  2008. An in vivo gene deletion system for determining temporal requirement of bacterial virulence factors. Proc Natl Acad Sci USA. 105:9385-90. (cited by Faculty 1000). PMID: 18599442

15. Banga, S., Gao, P., Shen X., Fiscus V., Zong W-X., Chen L. and Luo Z.-Q. 2007. Legionella
pneumophila inhibits macrophage apoptosis by targeting pro-death members of the Bcl2 protein family. Proc Natl Acad Sci USA. 104: 5121-5126. PMID: 17360363

14. Liu, Y. and Luo Z.-Q. 2007. The Legionella pneumophila effector SidJ Is required for efficient
recruitment of endoplasmic reticulum proteins to the bacterial phagosome. Infection and Immunity 75:592-603. PMID: 17101649

13. Conover G., Martinez-Morales F., Heidtman M., Luo Z.-Q.,Tang M., Chen C., Geiger O., and Isberg R. R. 2008 Phosphatidylcholine synthesis is required for optimal function of Legionella pneumophila virulence determinants.  Cell Microbiology 10:514-28. PMID: 17979985

12. VanRheenen, S. M. Luo Z.-Q., O’Connor, T. and Isberg R. R.  2006. Members of a Legionella
pneumophila family of proteins with ExoU/phospholipase A active sites are translocated to target cells. Infection and Immunity. 74: 3597-606. PMID: 16714592

11. Luo, Z.-Q. and Isberg R. R. 2004. Multiple substrates of the Legionella pneumophila Dot/Icm system identified by interbacterial protein transfer. Proc Natl Acad Sci USA. 101:  841-846. (cited by Faculty 1000). PMID: 14715899

10. Qin, Y, Luo Z.-Q, Farrand S. K. 2004. Domains formed within the N-terminal region of the quorum- sensing activator TraR are required for transcriptional activation and direct interaction with RpoA from Agrobacterium. Journal of Biological Chemistry.  279:40844-51

9. Luo, Z.-Q., Su S. and Farrand S. K.  2003.  In situ activation of the quorum-sensing transcription factor TraR by cognate and non-cognate acyl-Homoserine lactone ligands: kinetics and consequences. Journal of Bacteriology 185: 5665-5672.

8. Luo Z.-Q, Smyth AJ. Gao P, Qin Y, Farrand S. K. 2003. Mutational analysis of TraR: Correlating function with molecular structure of a quorum-sensing transcriptional activator. Journal of Biological Chemistry 278:13173-82.

7. Luo Z.-Q. and Farrand S. K. 2001.  The Agrobacterium tumefaciens rnd homolog is required for TraR-mediated quorum-dependent activation of Ti plasmid tra gene expression. Journal of Bacteriology 183:3919-3930.

6. Luo Z.-Q., Clemente T., and Farrand S. K. 2001. Construction of a derivative of Agrobacterium tumefaciens C58 that does not mutate to tetracycline resistance.  Molecular Plant-Microbe Interaction 14:98-103.

5. Qin Y., Luo Z.-Q., Smyth A. J., Gao P., Beck Von Bodman S., Farrand S. K. 2000. Quorum-sensing signal binding results in dimerization of TraR and its release from membranes into the cytoplasm.  The EMBO Journal 19:5212-5221.

4. Luo Z.-Q., Qin Y., and Farrand S. K. 2000. The antiactivator TraM interferes with the autoinducer-dependent binding of TraR to DNA by interacting with the C-terminal region of the quorum-sensing activator.  Journal of Biological Chemistry 275:7713-7722.

3. Luo, Z.-Q. and Farrand, S. K. 1999. Signal-Dependent DNA binding and functional domains of the quorum-sensing activator TraR as identified by repressor activity.  Proc Natl Acad Sci USA.  96: 9009-9014.

2. Luo, Z.-Q. and Farrand, S. K. 1999.  Cloning and characterization of a tetracycline resistance determinant present in Argobacterium tumefaciens C58.  Journal of Bacteriology 181: 618-626.

1. Hwang I., Smyth A., Luo Z.-Q., and Farrand S. K.  1999.  Modulating quorum-sensing: The antiactivatorTraM inhibits TraR-activation of Ti plasmid conjugal transfer by protein-protein interaction.  Molecular Microbiology 34: 282-294.