Nodamuravirus
Flock House Virus (FHV) is a small, simple, RNA insect virus. Comparison with the
high resolution structure of FHV indicates regions of icosahedrally-arranged RNA
density in the map. FHV most likely undergoes an infection process similar to
that of poliovirus.
Cover of Structure Vol2(4), April 1994. This is the structure of
Flock House Virus (FHV) solved by a combination of cryo-electron microscopy and
X-ray crystallography. The FHV model in the center is superimposed over the
two types of raw data used to compute the model: a transmission electron
micrograph of virus particles (green region) and an X-ray diffraction pattern of a virus crystal (bright spots against a brown background). The protein shell
of FHV (blue) is computationally trimmed away to visualize the internal
components including the viral RNA (red) and several a
-helical g-peptides (cyan, red and green
cylinders) which lie just inside the protein shell. These peptides interact with
the viral RNA and act to control capsid assembly and viral uncoating.
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Created by Shelly Bernardon